New perspectives on MAFLD

Fatty liver disease is a condition characterised by a build-up of fat in the liver and is the most common chronic liver disease that affects over one billion people. Over time, this can lead to complications including cirrhosis, liver failure, liver cancer, and heart health issues. The disease is now known as metabolic (dysfunction) associated fatty liver disease (MAFLD). This is because the disease is now understood to be linked to metabolic factors, such as obesity, insulin resistance, and diabetes.

MAFLD is a multisystem disorder with a heterogeneous disease course and outcomes. This means that it can affect multiple organs, and the course of the disease can vary from person to person. Some people with MAFLD may have no symptoms, while others may develop serious complications, such as liver cirrhosis or liver cancer. The diagnosis of MAFLD is often delayed, sometimes for decades. This is because the disease is often asymptomatic in the early stages. Additionally, there is no single test that can definitively diagnose MAFLD.

ON SALE! Charles Darwin Signature T-shirt – “I think.” Two words that changed science and the world, scribbled tantalizingly in Darwin’s Transmutation Notebooks.

Early diagnosis of MAFLD is essential for effective treatment. This is because early treatment can help prevent the disease’s progression and the development of complications. Many pharmacological and non-pharmacological treatments can be more effective in early disease. For example, lifestyle changes, such as losing weight, eating a healthy diet, and exercising regularly, can help to improve liver function and reduce the risk of complications.

It is important to stratify patients to develop effective treatments. This means grouping patients based on their individual characteristics, such as their disease severity, complications risk, and treatment response. This will help to ensure that patients receive the most appropriate treatment for their individual needs.

Sign up for the Daily Dose Newsletter and get every morning’s best science news from around the web delivered straight to your inbox? It’s easy like Sunday morning.

Success! You're on the list.

A new set of diagnostic criteria for MAFLD has been developed. An international group of experts developed these criteria to help in addressing these issues. The criteria apply to all ages and consider age-related factors. This means that they can be used to diagnose MAFLD in people of all ages, from children to adults.

The new diagnostic criteria for MAFLD have met their promise. This is because they are accurate and reliable in diagnosing MAFLD and idenftying the patients at high risk of disease complications.

The development of the new criteria has created a positive momentum for change. This is because it has led to increased awareness of MAFLD and has paved the way for further research and clinical trials. Therefore, the new criteria represent a significant step forward in diagnosing and treating this disease.


If you enjoy the content we create and would like to support us, please consider becoming a patron on Patreon! By joining our community, you’ll gain access to exclusive perks such as early access to our latest content, behind-the-scenes updates, and the ability to submit questions and suggest topics for us to cover. Your support will enable us to continue creating high-quality content and reach a wider audience.

Join us on Patreon today and let’s work together to create more amazing content!

DAILY DOSE: World leaders talk climate change; March of the microscopic robots.
TALK TALK TALK. The international climate talks in Dubai highlighted the urgency …
50 States of Science: The New Mexico Museum of Natural History and Science is the states gem for the curious.
NUTSHELL: The New Mexico Museum of Natural History and Science is a …

Leave a Reply

%d bloggers like this: