V. cholerae resistance to CAMP deciphered

Cholera is a devastating disease for millions worldwide, primarily in developing countries, and the dominant type of cholera today is naturally resistant to one type of antibiotic usually used as a treatment of last resort. Researchers at the University of Georgia have now shown that the enzyme that makes the El Tor family of V. … Continue reading V. cholerae resistance to CAMP deciphered

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When it comes to actin, it’s the silent genes you have to look out for

Humans possess six forms of the protein actin, which perform essential functions in the body. Two in particular, β-actin and γ-actin, are nearly identical, only differing by four amino acids. Yet these near-twin proteins carry out distinct roles. A long standing question for biologists has been, how is this possible? "It's a mystery that's been … Continue reading When it comes to actin, it’s the silent genes you have to look out for

In the war between bacteria, resistance among the spoils

Bacteria not only develop resistance to antibiotics, they also can pick it up from their rivals. In a recent publication in Cell Reports, Researchers from the Biozentrum of the University of Basel have demonstrated that some bacteria inject a toxic cocktail into their competitors causing cell lysis and death. Then, by integrating the released genetic … Continue reading In the war between bacteria, resistance among the spoils

Time to think outside the pill box for minor infections

Got a sore throat? The doctor may write a quick prescription for penicillin or amoxicillin, and with the stroke of a pen, help diminish public health and your own future health by helping bacteria evolve resistance to antibiotics. It's time to develop alternatives to antibiotics for small infections, according to a new paper by scientists … Continue reading Time to think outside the pill box for minor infections

For cancer immunotherapy, two may be better than one

The Alliance for Cancer Gene Therapy (ACGT), a non-profit based in Stamford, Connecticut, dedicated to funding breakthrough cancer gene therapy treatments, has had its funding pay off with a promising study on breast cancer coming out of The Ottawa Hospital and the University of Ottawa in Ottawa, Canada. The study suggests that a combinations of … Continue reading For cancer immunotherapy, two may be better than one

Can CAR-T provide long term immunity to HIV?

Through gene therapy, researchers engineered blood-forming stem cells (hematopoietic stem/progenitor cells, or HSPCs) to carry chimeric antigen receptor (CAR) genes to make cells that can detect and destroy HIV-infected cells. These engineered cells not only destroyed the infected cells, they persisted for more than two years, suggesting the potential to create long-term immunity from the … Continue reading Can CAR-T provide long term immunity to HIV?

Cholera hotspots identified in Uganda

Uganda is among the countries is sub-Saharan Africa where cholera remains a recurring problem, despite advances in science and technology for prevention, detection and treatment of the infectious disease. Now, researchers reporting in PLOS Neglected Tropical Diseases have identified cholera hotspots around Uganda to help target interventions. Cholera, caused by ingestion of food or water … Continue reading Cholera hotspots identified in Uganda

The Patterned Landscape: Brigitte Caramanna’s nature etchings

Brigitte Caramanna’s etchings range from intimate cellular landscapes to vast, otherworldly stretches of rocky terrain. Other times, she draws on organic bursts embodied by the branching of a tree or the budding of a cell. Her prints can feel unsettling, the way film negatives do. Their inversion of colors suggest a phantasmagorical alternate reality. Yet, … Continue reading The Patterned Landscape: Brigitte Caramanna’s nature etchings

War once helped build nations, now it destroys thema

Organised violence – the term war boils down to – has long been a unifier of peoples. Archeological evidence shows that nearly half those who lived during the last part of the Stone Age in Nubia, an area along the southern reaches of the Nile River, died violent deaths. Many other tribal societies through the … Continue reading War once helped build nations, now it destroys thema