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DAILY DOSE: Authorities investigate Chinese TCM clinic after cancer deaths; House subcommittee report links SARS-CoV-2 to lab leak.

CHINESE CLINIC UNDER INVESTIGATION AFTER CANCER PATIENTS DIE

Chinese authorities are investigating the Yaowang Valley Traditional Chinese Medicine Clinic in Hubei province after at least 15 cancer patients died following treatment. The clinic’s founder, Wu Pengfei, falsely claimed to cure cancer using TCM and faced fines for illegal activities, including using unqualified staff and failing to maintain proper medical records. The clinic, which operated from April 18 to May 31, attracted 392 patients, with 20 falling seriously ill. Wu’s accomplice, Hou Yuanxiang, promoted the clinic with claims of an 80% cancer cure rate. However, patients experienced severe side effects, including fatigue and gastrointestinal issues, after undergoing treatments like “plum blossom moxibustion” and taking harmful “secret prescriptions.” One patient died after developing ascites. Public outrage grew, with social media users warning against alternative treatments. Authorities are continuing their investigation and plan to release findings soon. The clinic’s property is now deserted. (Channel News Asia)


FAST FOOD CHAINS EXPAND NEAR UK SCHOOLS AMID CRITICISM

Fast food chains like Subway, Domino’s, and KFC have rapidly expanded near schools in the UK, with nearly 1,000 new outlets opening since 2014. Subway alone has opened 420 locations within 400 meters of schools, while Domino’s and Greggs have added 354 and 329, respectively. This growth has increased the number of schools with nearby fast food outlets by 38%, now affecting 3,411 schools. Critics argue that these companies are targeting young customers to boost profits, contributing to childhood obesity. Health Secretary Wes Streeting condemned the practice, pledging government action to limit such openings. Research by Dr. Jody Hoenink shows that 76% of Domino’s branches are now near schools, and many chains like KFC, Greggs, and Starbucks have at least half their outlets in these areas. Experts warn this trend exacerbates health inequalities, particularly in disadvantaged areas, and ministers are considering restrictions on fast food outlets near schools. (The Guardian)



HOUSE REPORT LINKS SARS-COV-2 TO WUHAN LAB LEAK THEORY

After a two-year investigation, the House Select Subcommittee on the Coronavirus Pandemic released a report on December 2, 2024, claiming that SARS-CoV-2 likely originated from a lab leak at the Wuhan Institute of Virology (WIV), rather than through natural transmission. The report, based on over 30 interviews and more than 1 million documents, presents circumstantial evidence, including the WIV’s use of NIAID funds for “gain-of-function” research. It also reveals that the Department of Justice may have been investigating potential crimes related to the pandemic’s origins, though the DOJ has not confirmed this. Democrats on the panel contested the Republican conclusions, defending Dr. Anthony Fauci and challenging the claim that the viruses studied at WIV were linked to SARS-CoV-2. The report also criticized public health responses like masking, lockdowns, and vaccine mandates, while praising Operation Warp Speed for its role in vaccine development. The subcommittee will formally approve the report tomorrow. (Science)


NEW ANALYSIS LINKS HUA NAN MARKET TO COVID-19 ORIGINS

Researchers have re-analyzed data from Wuhan’s Huanan Seafood Wholesale Market, providing new clues about the origin of the COVID-19 pandemic. Their analysis suggests that animals at the market were infected with a virus, supporting the theory that the market played a key role in the virus’s transmission to humans. The findings, presented in December 2024, show evidence of immune responses in raccoon dogs and greater hog badgers, animals susceptible to SARS-CoV-2. This new data adds to earlier studies linking the market to early COVID-19 cases, though the specific virus responsible remains unclear. While most researchers agree that SARS-CoV-2 likely originated in animals, some still argue that it may have escaped from a lab, as suggested by a recent report from a U.S. House committee. Despite indirect evidence, researchers continue to seek direct confirmation of the virus in infected animals at the market to fully resolve the origin story. (Nature)


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WADA IGNORES WARNING OF STATE-BACKED DOPING IN CHINA

In 2020, WADA’s investigative unit warned top officials about a potential state-backed doping program in China, based on a doctor’s claims that athletes used undetectable levels of trimetazidine (TMZ) to enhance performance. The doctor, who had defected in 2017, outlined a systematic doping effort, including the use of TMZ to boost stamina. Despite the alarm, WADA’s leadership chose not to act after 23 Chinese swimmers tested positive for TMZ in 2021. Instead of pursuing further investigation, they cleared the swimmers, accepting China’s explanation of contamination from food, which lacked credible evidence. This decision raises concerns about WADA’s response to Chinese doping, following the 2015 Russian doping scandal. The incident has sparked further scrutiny of WADA, with the U.S. delaying funding and the Justice Department opening an investigation. Meanwhile, the 2017 doctor’s testimony and WADA’s failure to act highlight ongoing challenges in addressing state-sponsored doping in global sports. (New York Times)


STUDY FINDS CHLORINE INEFFECTIVE AGAINST CRYPTOSPORIDIUM IN SPLASH PADS

A study published in Morbidity and Mortality Weekly Report found that chlorine, commonly used in splash pads for disinfection, is ineffective at eliminating Cryptosporidium, a parasite responsible for most waterborne disease outbreaks linked to these recreational spaces. Splash pads, designed without standing water to reduce drowning risks, have been associated with waterborne outbreaks of infectious diseases since their emergence in the 1990s. The study reviewed 60 outbreaks from 1997 to 2022 across 23 states and Puerto Rico, resulting in 10,611 cases, 152 hospitalizations, and 99 emergency visits. Cryptosporidium was responsible for 90% of these cases, including three large outbreaks. Other pathogens like norovirus and Shigella also contributed. The study emphasizes that chlorine does not affect Cryptosporidium, and behavior interventions—such as monitoring children for diarrhea and ensuring proper diaper hygiene—are key to preventing these outbreaks, especially since many splash pads are exempt from public health regulations. (CIDRAP)


AI STRUGGLES WITH ADVANCED MATH PROBLEMS DESPITE PROGRESS

Recent advancements in artificial intelligence (AI) have shown impressive results in solving math problems, yet the field remains far from having AI rival human mathematicians in frontier research. A recent study by Epoch AI tested six top large language models (LLMs) on a series of difficult, original math problems designed by expert mathematicians. The models failed miserably, answering fewer than 2% of the questions correctly. While current AI math benchmarks are typically geared towards high school or undergraduate-level math, real mathematical research involves far more complex problems, such as unsolved questions about prime numbers. AI’s performance is also affected by data contamination, as these models are trained on vast amounts of internet data, potentially exposing them to solutions. Despite these limitations, many experts believe AI will eventually catch up, but others worry about its social impacts, including potential exclusivity in access and the shifting roles of mathematicians. (Science)


HOKKAIDO SEES SURGE IN BEAR CAPTURES DUE TO FOOD SHORTAGE

In fiscal 2023, Hokkaido recorded a significant increase in the capture or hunting of “higuma” brown bears, with 1,804 bears removed, nearly double the number from the previous year. The rise in bear activity was attributed to a shortage of acorns and other food sources in the mountain forests, pushing the bears to search for food in agricultural areas. As a result, many bears caused crop damage, prompting the prefectural government to create a manual for municipalities to identify and manage “problematic” bears. Of the 1,804 bears, 746 were female, and 1,684 were captured due to crop damage. The remaining 120 were hunted. The increase in bear sightings and captures was linked to their expanded foraging range as food became scarcer in the wild. (Asahi Shinbun)


ANCIENT SPA SITE IN TUSCANY REVEALS REMARKABLE ARTIFACTS

Remarkable discoveries have emerged from an ancient thermal spa site in San Casciano dei Bagni, Tuscany, dating back to the second century BC. Excavations led by Jacopo Tabolli have uncovered a wealth of artifacts, including bronze snakes, statues, two gold crowns, jewelry, thousands of coins, and perfectly intact eggs, preserved by the warm waters and mud of the springs. The site, initially built by the Etruscans and later used by Romans, was a place of worship and ritual. Key finds include a 1-meter long bronze snake, thought to represent the Good Spirit, and a votive offering of a male body cut in half. The spa, frequented by emperors like Augustus, was closed in the 5th century AD during Christian times, but the offerings were left undisturbed. The artifacts will be displayed in a museum slated to open in San Casciano dei Bagni in 2026. (The Guardian)


VOYAGER PROBES CONTINUE TO SEND DATA AFTER 45 YEARS

The Voyager probes, launched in 1977, have revolutionized our understanding of the outer planets and continue to send data, even after more than 45 years. Initially tasked with studying Jupiter, Saturn, Uranus, and Neptune, the probes provided groundbreaking images and data, revealing stunning planetary features like Jupiter’s atmosphere, Uranus’s magnetic field, and Saturn’s rings. They discovered new moons, active volcanoes, and icy surfaces, challenging prior assumptions about these worlds. After completing their planetary mission in 1990, the probes continued to relay valuable information about the solar system’s outer reaches and interstellar space. However, with their nuclear batteries running low, their communication with Earth will soon end. NASA engineers have been shutting down non-essential instruments to extend their life, and experts predict they will lose contact within the next five years. Both probes carry golden records with sounds and images of Earth, destined to be discovered by alien civilizations in the distant future, ensuring their legacy endures long after their silence. (Nautilus)

Thanks for reading. Let’s be careful out there.

WORDS: The Biology Guy.


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